Informatics Publishing Limited

D. C. Chaudhari , C. L. Goel , R. K. Suri , P. K. Deshmukh

Abstract

The essential oil obtained from the leaves of newly evolved Eucalyptus hybrid FRI-5 as such and at varied dilutions viz., 1: 100, 1 : 250, 1 : 500 and 1 : 1000 bas been tested for its antimicrobial activity in-vitro against eight bacteria viz., Bacillus mycoides, B. pumilus, Escherichia coli, Proteus vulgaris, Salmonella paratyphii, Sarcina lutea, Shigella nigesta, Staphylococcus aureus and six fungi viz., Aspergillus niger, Candida albicans, Epidermophyton rubrum, Malbranchea pulchella, microsporum, gypseum, Penicillium notatum. The present investigations indicate that the Eucalyptus hybrid FRI-5 essential oil has potent antifungal as well as antibacterial efficacy being maximum when it is undiluted. The activity decreases as the dilution increase. Even at dilution of 1 : 1000) tbe oil bas been found active against all the test organisms.

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S. A. Phatangare ¹, P. K. Deshmukh ¹, R. A. Deshmukh ¹

Affiliations
1 Department of Computer Engineering, Rajarshi Shahu College of Engineering, University of Pune, Tathawade-411033, Pune, IN

Abstract

Public-key cryptography refers to a cryptographic system requiring two separate keys, one of which is secret and one of which is public.Cloud Computing has great potential of providing robust computational power to the society at reduced cost. It enables customers with limited computational resources to outsource their large computation workloads to the cloud, and economically enjoy the massive computational power, bandwidth, storage, and even appropriate software that can be shared in a pay-per-use manner. Despite the tremendous benefits, security is the primary obstacle that prevents the wide adoption of this promising computing model, especially for customers when their confidential data are consumed and produced during the computation. Treating the cloud as an intrinsically insecure computing platform from the viewpoint of the cloud customers, we must design mechanisms that not only protect sensitive information by enabling computations with encrypted data, but also protect customers from malicious behaviors by enabling the validation of the computation result. Focusing on engineering computing and optimization tasks, we investigates secure outsourcing of widely applicable linear programming (LP) computations. In order to achieve practical efficiency, our mechanism design explicitly decomposes the LP computation outsourcing into public LP solvers running on the cloud and private LP parameters owned by the customer. To validate the computation result, we explore the fundamental duality theorem of LP computation and derive the necessary and sufficient conditions that correct result must satisfy. In the proposed algorithm, the robustness preference of the output given by the server is checked by the client, whether the server is given the correct output. Whether the cloud is giving the correct result we also try to device the robust algorithm for numerical stability.

Keywords

LP Parser, LP Definition Creater, Public Cryptography, RSA Algorithm, Robust Algorithm.

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Ganesh B. Patil ¹, P. K. Deshmukh ², V. S. Belgamwar ¹

Affiliations
1 Department of Pharmaceutics, R.C.Patel College of Pharmacy, Near Karwand Naka, Shirpur, Dist-Dhule-425405, Maharashtraa, IN
2 H.R.Patel Women's College of Pharmacy, Near Karwand Naka, Shirpur, Dist-Dhule-425405, Maharashtra, IN

Abstract

The present study is aimed at improving the dissolution of poorly water soluble Aceclofenac by complexation with β-cyclodextrin and Hydroxypropyl- β-cyclodextrin. Bioavailability of such drug may be enhanced by improving its solubility and dissolution rate. The objective of present study is to increase the solubility and dissolution rate of Aceclofenac by preparing its occlusion complexes with β-cyclodextrin and Hydroxypropyl-β-cyclodextrin in different molar ratios using kneading method. The prepared complexes were characterized for drug content, differential scanning calorimetry, FTIR spectral studies, phase solubility and in-vitro dissolution profile. DSC and FTIR spectral studies performed on solid complexes have confirmed the inclusion complexation between drug and Cyclodextrins. It has been observed that solubility and dissolution rate increased to greater extent for Hydroxypropyl-β-cyclodextrin than β-cyclodextrin and that of pure drug.

Keywords

Aceclofenac, β-Cyclodextrin, Hydroxypropyl-β-Cyclodextrin, Inclusion Complex, DSC, FTIR, Solubility, Dissolution Enhancement.

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